methylation homocysteine MTHFR

METHYLATION CYCLE

Methylation

Methylation cycle is a biochemical pathway transferring methyl group (-CH3) in the metabolism of nucleic acids and proteins.

Methylation cycle regulates our body physiology activities, which includes DNA synthesis and repair, gene regulation, neurotransmitter production, hormone regulation, energy 

production, fat metabolism and immune function.

Mehtylation folate cycle
Homocysteine hyperhomocysteinemia
Homocysteine

Homocysteine is an amino acid produced when proteins are broken down. Deficiency of nutrients e.g folate will cause elevation of homocysteine in blood plasma.

Hyperhomocysteinemia (>12µmol) is associated with health conditions e.g. cardiovascular and cerebrovascular diseases, psychiatric disorders and poor pregnancy outcomes.